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cardinal  (cardinals plural )
1  n-count; n-title A cardinal is a high-ranking priest in the Catholic church. 
In 1448, Nicholas was appointed a cardinal...  
2  adj A cardinal rule or quality is the one that is considered to be the most important. 
FORMAL 
(=chief, principal) 

As a salesman, your cardinal rule is to do everything you can to satisfy a customer...  
3  n-count A cardinal is a common North American bird. The male has bright red feathers. 
cardinal number   (cardinal numbers plural )A cardinal number is a number such as 1, 3, or 10 that tells you how many things there are in a group but not what order they are in. Compare  ordinal number.  n-count 
cardinal point   (cardinal points plural )The cardinal points are the four main points of the compass, north, south, east, and west.  n-count 
cardinal sin   (cardinal sins plural )If you describe an action as a cardinal sin, you are indicating that some people strongly disapprove of it.  n-count 
I committed the physician's cardinal sin: I got involved with my patients.