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tire  (tires 3rd person present) (tiring present participle) (tired past tense & past participle )
1  verb If something tires you or if you tire, you feel that you have used a lot of energy and you want to rest or sleep. 
If driving tires you, take the train...  V n 
2  verb If you tire of something, you no longer wish to do it, because you have become bored of it or unhappy with it.  (=weary) 
He felt he would never tire of international cricket...  V of n/-ing 
3  n-count A tire is the same as a  tyre. 
 (AM) tire out  phrasal verb If something tires you out, it makes you exhausted.  (=wear out) 
The oppressive afternoon heat had quite tired him out...  V n P 
 tired out  adj 
He was obviously tired out.