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1    an ancient city in Mesopotamia, on the River Tigris: founded by Seleucus Nicator in 312 b.c.; became the chief city of the Seleucid empire; sacked by the Romans around 162 a.d  
2    an ancient city in SE Asia Minor, on the River Calycadnus (modern Goksu Nehri): captured by the Turks in the 13th century; site of present-day Silifke (Turkey),   (Official name)    Seleucia Tracheotis   Trachea  
3    an ancient port in Syria, on the River Orontes: the port of Antioch, of military importance during the wars between the Ptolemies and Seleucids; largely destroyed by earthquake in 526; site of present-day Samandag (Turkey),   (Official name)    Seleucia Pieria  
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