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1    a person, horse, vehicle, etc., used in a race or speed trial to set the pace  
2    a person, an organization, etc., regarded as being the leader in a particular field of activity  
3      (Also called)    cardiac pacemaker   a small area of specialized tissue within the wall of the right atrium of the heart whose spontaneous electrical activity initiates and controls the beat of the heart  
4      (Also called)    artificial pacemaker   an electronic device for use in certain cases of heart disease to assume the functions of the natural cardiac pacemaker  
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